Date of Publication :7th September 2017

Abstract: The retina is the only part of the human body where the blood circulation can be observed directly. Several systemic diseases can affect the retinal blood vessels, which makes the retinal image analysis a potential diagnostic tool, as it allows assessing vascular changes in an easy and non-invasive way. Retinal image analysis is one of the active research areas with the goal of providing computer-aided methods to help the quantification, measurement and visualization of retinal landmarks and biomarkers. In diabetic retinopathy (DR), the blood vessels often show abnormalities at early stages [1], as well as vessel diameter alterations [2]. Changes in retinal blood vessels, such as significant dilatation and elongation of main arteries, veins, and their branches [2, 3], are also frequently associated with hypertension and other cardiovascular pathologies.

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