International Journal of Engineering Research in Computer Science and Engineering (IJERCSE)

Early detection of Alzheimerâ€™s using blood plasma proteins with Recurrent Neural Networks

Author : Monisha M ¹ Harshitha K M ² Dhanalakshmi N H ³ Kokatam Sai Prakash Reddy ⁴ Nagarathna C R ⁵ Dr. Kusuma M ⁶

Date of Publication :1st December 2022

Abstract: Alzheimer's disease (AD) which is a disease that belongs to the group of neurodegenerative diseases and is considered one of the most destructive and severe diseases of the human nervous system. Presently there is no quick cost-effective method for routinely screening of persons with Alzheimer's disease. The problem is how to diagnose it at the earliest possible stage before specific symptoms begin to appear. The main idea is to build an intelligent system that will be able to answer, based on certain biomarkers from the subject, whether the disease is present or not. This paper presents how machine learning concepts are used that have upgraded the detection of Alzheimerâ€™s disease in the early stage. In addition, the proposed does hierarchal classification into stages: CN, EMCI, LMCI and AD. Experimental results show that the proposed method achieves classification accuracy of 92-95 % for AD demonstrating the promising performance for RNN analysis.

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