Author : Shrinithi Natarajan 1
Date of Publication :5th May 2023
Abstract: Genes make proteins according to a simple genetic code but not all proteins are made in every single cell. It appears we have another layer of coding to tell a cell what proteins to make and when to make those proteins. The nucleosomes which form because of compact wrapping of DNA around histones does this extra coding. A function of the nucleosomes apart from compacting DNA is hiding genes from the cell. The spools can find the right places on the DNA to hide all the unnecessary genes. We have aimed to find a probabilistic approach to map or trace the pattern that the sequencing of the genome most closely follows so that we can use this very path to mask or unmask a gene expression. We used the Viterbi algorithm to trace the same.